Cardiovascular Diseases, Heart Diseases, Heart Failure
Conditions
Brief summary
In this study the ability of smartphone sensors (accelerometer and gyroscope) to identify patients with heart failure will be studied.
Detailed description
Heart Failure (HF) is a condition where heart is unable to maintain adequate volume of blood in circulation corresponding to prevailing physiological demand. Gyrocardiography is a technique that utilizes micro electromechanical sensors (MEMS), accelerometer and gyroscope, to detect vibrations and rotation of thorax caused by cardiac motion. The main purpose of this study is to test the ability of an app of a smartphone with embedded motion sensors, positioned on the chest which measures the movements and function of the heart, to identify patients with different types of heart failure and their characteristics, as compared with clinical diagnosis. Echocardiography will also be used to confirm changes in cardiac cardiac mechanics including strain, cardiac torsion, diastolic filling characteristics.
Interventions
None listed
Sponsors
Turku University Hospital
Helsinki University Central Hospital
Precordior Ltd
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>18 years * Patients visiting hospital for heart failure, either outpatient clinic or cardiac ward * Signed informed consent as an acceptance to participate to the trial
Exclusion criteria
* Age \<18 years * Severe cardiac valve disease * Previous prosthetic cardiac valve * Major adverse cardiovascular event or surgery within 6 weeks of planned study enrollment * Patients with pacemaker * Informed consent form not signed.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HF specific motion sensor characteristics validation against echocardiography and other clinical features | From the hospital admission to study closure visit, on average 15 weeks | The study aims to validate HF specific characteristics obtained with accelerometer (m/s2) and gyroscope (degree/s) against the current gold standard, detailed echocardiography examination in individuals already diagnosed with HF. Data of anonymised subjects without diagnosed or suspected HF will be used as controls to study the detection of HF. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| HF decompensation specific motion sensor characteristics validation | 14 weeks | The ability of the motion sensors to detect differences in myocardial mechanics in patients with decompensation episode compared to patients without decompensation episode, assessed by receiver operating characteristics (ROC). |
Countries
Finland
Outcome results
None listed