Impact of OCT Imaging on Decision Making During PCI in ACS Patients

Impact of Optical Coherence Tomography Imaging on Decision-making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04444037

Enrollment

390

Registered

2020-06-23

Start date

2019-01-01

Completion date

2020-04-30

Last updated

2020-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Keywords

OCT, stent implantation

Brief summary

Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.

Detailed description

OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.

Interventions

DEVICEOCT-guided PCI

using optical coherence tomography imaging to help PCI procedure

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients presented with acute coronary syndrome. * PCI was done to them with stent implantation.

Exclusion criteria

* Multivessel PCI at the index procedure. * Patients with ACS due to graft failure post CABG. * Patients treated with no stent implantation.

Design outcomes

Primary

Measure	Time frame	Description
Percent difference in lumen expansion in stent treated lesion	Immediately after the procedure	Compare residual percent diameter stenosis, percent area stenosis, and acute lumen gain between the two groups.

Secondary

Measure	Time frame	Description
Clinical outcomes at 1 year follow up	During 1 year following the index procedure	Cardiac death, MI, clinical-driven target-lesion revascularization (TLR), and stroke

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026