SARS-CoV2
Conditions
Keywords
SARS-CoV2, COVID-19, Serology, Hospital workers, Children
Brief summary
The purpose of this study is to define seroprevalence of anti-SARS-CoV2 among children of Hospital Workers in APHP, particularly exposed population, according to parents' SARS-CoV2 serological status.
Interventions
BIOLOGICALSerology SARS-CoV2
Collect serum for Serology SARS-CoV2 at inclusion
BEHAVIORALData collection
Collect clinical and demographic data, habitus, Lifestyle Counseling at inclusion
Sponsors
URC-CIC Paris Descartes Necker Cochin
Assistance Publique - Hôpitaux de Paris
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
Hospital workers : 1. Individuals aged over 18, having a professional activity at the APHP (employees, interns, volunteers) 2. Affiliated to a social security regimen 3. Have at least one child under the age of 18 living in the same house. 4. have signed consent Child (ren), spouse and other member (s) residing at household: Child (ren), spouse and any other member residing in the household of a professional of the Paris Center Hospitals meeting the inclusion criteria above.
Exclusion criteria
Refuse to participate in research
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Seroprevalence of antibodies anti- SARS Cov2 in blood sample of children of Hospital workers | at inclusion | Percentage of children with seropositive in blood sample according to parents' SARS Cov2 serological status |
| Seroprevalence of antibodies anti- SARS Cov2 in saliva sample of children of Hospital workers | at inclusion | Percentage of children with seropositive according in saliva sample to parents' SARS Cov2 serological status |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of different clinical symptoms in children with a positive serology | At inclusion | — |
| Serological result of each member of the family | At inclusion | — |
| Number of spouses of hospital workers with a positive serology | At inclusion | — |
| Number of Asymptomatic Children with a positive seroloy | At inclusion | — |
| Number of severely symptomatic spouses of hospital workers with a positive serology | At inclusion | — |
| Comparison of Serological result obtained in blood and saliva samples | At inclusion | — |
| Risk factors based on a questionnaire for children and adults | At inclusion | the following factors will be of particular importance: characteristics and composition of the family home, barrier measures, medical history and comorbidities. |
| Number of Asymptomatic spouses of hospital workers with a positive serology | At inclusion | — |
| Number of severely symptomatic Children with a positive serology | At inclusion | — |
Countries
France
Outcome results
None listed