Respiratory Insufficiency
Conditions
Brief summary
comparing high flow nasal cannula , conventional oxygen tharapy and non invasive ventilation post-extubation period for patients mechanically ventilated due to respiratory failure regarding re-intubation rate, ICU outcome & 28 days mortality
Detailed description
patients with respiratory failure either type I or type II planned for extubation will be divided into 3 groups post extubation : Group I: will receive high flow nasal cannula giving oxygen 60 litres / minute flow group II: will receive nasal cannula up to 10 litres / minute group III: will receive non invasive ventilation Data of the patients will be collected for 28 days post-extubation and analysed
Interventions
DEVICEHigh flow nasal cannula
Device gives high flow oxygen comparable to non invasive ventilation and conventional oxygen therapy
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* respiratory failure type I and Type II
Exclusion criteria
* Mechanical ventilation due to other cause such as disturbed conscious level or respiratory muscle weakness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with post extubation respiratory failure | 7 days | Number of participants with post extubation hypoxemia with or without hypercapnea |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of ICU stay and mortality | 28 days | Duration of ICU stay and incidence of mortality |
Countries
Egypt
Outcome results
None listed