Parkinson Disease
Conditions
Keywords
continous dopaminergic delivery device, deep brain stimulation, sleepiness
Brief summary
Sleepiness is frequent in parkinsonian patients, increasing with the duration of disease. By patients with motor fluctuations, continuous dopaminergic delivery devices or deep brain stimulation are justified to improve the motor prognosis. Antiparkinsonian treatments, especially dopaminergic agonists, may worsen the sleepiness and thus affect the quality of life. The investigators aimed to monitor sleepiness in parkinsonian patients before and during treatment with continous dopaminergic delivery device or deep brain stimulation.
Interventions
DIAGNOSTIC_TESTMultiple sleep latency tests
The investigators measure the objective sleepiness by recording the electro-encephalogramm during four experimental diurnal naps. They also perform a nocturnal polysomnography prior to the tests for a better interpretation.
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patient with Parkinson's disease and motor fluctuations * and indicated for a continuous dopaminergic delivery device or deep brain stimulation
Exclusion criteria
* age \< 18 years * refusal for the continuous dopaminergic delivery device or deep brain stimulation * wake-promoting drugs intake * refusal to participate * legal protection * uncontrolled sleep apnea
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean sleep latency | before continuous antiparkinsonian treatment | Algebric mean (in minutes) of the sleep latency for the four experimental naps |
Countries
France
Contacts
Primary ContactNicolas Carpentier
Outcome results
None listed