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Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04437758
Enrollment
50
Registered
2020-06-18
Start date
2019-08-22
Completion date
2020-02-05
Last updated
2020-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Collagen Synthesis, Rate of Force (RFD) Development

Keywords

exercise, performance, athletes

Brief summary

Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes

Interventions

DIETARY_SUPPLEMENTCollagen and Vitamin C powder mix nutritional intervention

20 g collagen + 50 mg vitamin C daily, 60 min prior to exercise

OTHERMaltodextrin placebo powder

20 g maltodextrin placebo daily, 60 min prior to exercise

OTHERMaximum power training exercise

Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)

Sponsors

PepsiCo Global R&D
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

Sealed opaque packets coded by Sponsor's Product Development

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

1. Healthy male athletes between 18-30 years of age 2. Currently participating in sport 3. \<3 musculoskeletal injuries in the past year 4. No health or dietary restriction that would be affected by the supplementation protocol

Exclusion criteria

1. History of more than 3 musculoskeletal injuries within the past 12 months 2. Health, dietary restriction or diet that would be affected by the supplementation protocol 3. Willing to eat similar dietary pattern the day before baseline testing and each exercise testing/intervention day

Design outcomes

Primary

MeasureTime frameDescription
Maximal rate of force development (RFD) of isometric squat (MIS)% change from baseline to week 1, week 2 and week 3Force (N) over time (msec) for the maximum slope of the first 20% of the movement
Counter-movement jump (CMJ) rate of force development (RFD)% change from baseline to week 1, week 2 and week 3CMJ jump performance N/s/kg
Squat jump height rate of force development (RFD)% change from baseline to week 1, week 2 and week 3Squat jump height performance RFD/kg

Other

MeasureTime frameDescription
Maximum peak force of maximal isometric squat (MIS)% change from baseline to week 1, week 2 and week 3Peak force (N)
Leg stiffness assessment% change from baseline to week 1, week 2 and week 3Tendon stiffness mean per kg (N/m/kg)
Counter-movement jump (CMJ) net eccentric impulse% change from baseline to week 1, week 2 and week 3Jump performance max N/s/kg (Note: Eccentric is the drop down part of the CMJ)
Counter-movement jump (CMJ) net concentric impulse% change from baseline to week 1, week 2 and week 3Jump performance max N/s/kg (Note: Concentric is the movement upwards of the CMJ)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026