Effects of Exercise Intensity on Energy Intake, Appetite and Enjoyment in Overweight and Obese Females

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04437550

Enrollment

Registered

2020-06-18

Start date

2016-01-31

Completion date

2016-08-31

Last updated

2020-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and Obesity

Brief summary

Interval exercise involves short bouts of high intensity exercise interspersed with periods of lower intensity exercise. The benefit is that a shorter total duration of exercise may be required to achieve cardiovascular benefits similar to or even superior to traditional longer bouts of steady state endurance exercise. However how this type of exercise affects appetite and energy intake, particularly in overweight and obese females is not well known. This study involves two trials of exercise, one at high intensity and one at low intensity, followed by a buffet lunch, in overweight and obese females.

Interventions

OTHERExercise

high intensity exercise = 15 x 60 s sprints at 85% velocity of VO2max (vVO2max) with 60 s walking at 20% vVO2max or moderate intensity exercise = walking at 60% vVO2max

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

1. Female 2. Adult 3. apparently healthy 4. overweight or class I obese 5. eumenorrheic

Exclusion criteria

1. Diabetes 2. pregnancy 3. cardiovascular disease 4. greater than 1 hour of structured physical activity per week 5. thyroid disease 6. polycystic ovary disease

Design outcomes

Primary

Measure	Time frame	Description
Change in energy expenditure	immediately pre-breakfast, immediately pre-exercise, during exercise, and immediately post-exercise.	caloric expenditure measured via indirect calorimetry
Change in energy intake	immediately post exercise	measured via standardized lunch
Change in appetite	immediately pre-breakfast, immediately post-breakfast, immediately post-exercise and immediately pre-lunch	measured via circulating hormones leptin and acylated ghrelin
Change in subjective hunger	baseline, immediately pre-exercise, immediately post-exercise, immediately pre-lunch, and immediately post-lunch	via visual analogue scale 100 mm, higher scores indicate greater hunger

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026