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Evaluation of Functions of Swallowing and Voice in Ankylosing Spondylitis Patients

Evaluation of Functions of Swallowing and Voice in Ankylosing Spondylitis Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04437394
Enrollment
60
Registered
2020-06-18
Start date
2018-06-30
Completion date
2018-10-30
Last updated
2020-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis, Swallowing Disorder.Other Specified, Voice Alteration

Keywords

Ankylosing spondylitis, swallowing, voice

Brief summary

In this study was to determine whether changes that occurred over time had an impact on the swallowing and voice functions depend of Ankylosing spondylitis patients.

Detailed description

This study was carried out at the University of Health Sciences Okmeydani Training and Research Hospital, Department of Otorhinolaryngology. Study was performed on 30 patients and 30 healthy subjects (Group 2) who were diagnosed with ankylosing spondylitis using modified New York criterion. The patients were asked to fill the EAT-10 and flexible endoscopic swallowing evaluation was performed. Voice recordings were taken from the patients to evaluate the voice disturbance and acoustic evaluation was taken with PRAAT program.

Interventions

The patients were assessment with flexible endoscopic swallowing evaluation was performed with colored pudding.

DIAGNOSTIC_TESTThe analysis of voice

Voice recordings were taken from the patients to evaluate the voice disturbance and acoustic evaluation was taken with PRAAT program.

Sponsors

Yavuz Atar
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Diagnosed with Ankylosing spondylitis * Person who accept to consent form

Exclusion criteria

* Pulmoner diseases * Laryngeal polip or nodules * Underwent to larynx or esophageal surgery * Central nerve system diseases

Design outcomes

Primary

MeasureTime frameDescription
Quality of swallowing3 monthsQuality of swallowing was assessed by Eating Assessment Tool inventory consisting in 10 questions that scores from 0 to 40. Low score is better, higher score is worse.
Values of aspiration3 monthsAspiration was assessed by aspiration penetration scale during swallowing with flexible endoscopy. The scale consisting in 8 degree that scored from 1 to 8. Higher score is worse.
Voice analysis3 monthsVoice recordings were analyzed by PRAAT computer software. The investigator measured to shimmer, jitter and HNR voice values. The values are variation of frequency and amplitude of the sound wave. Higher value shows healthy voice for HNR parameters, lower value shows healthy voice for shimmer and jitter.
Cervical spine situation3 monthsCervical spine was assessed with modify stoke ankylosing spondylitis spine score that scored from 0 to 3. Low score is better and high score is worse.
Ankylosing spondylitis disease activity3 monthsThe investigator measured to disease activity with bath ankylosing spondylitis disease activity index consisting in 6 questions that scored from 0 to 10 and morning rigidity times. Low scores are better and high scores are worse.

Secondary

MeasureTime frameDescription
Demographic values3 monthsDemographic values were assessed as age (18-70) ,education and gender (male or female).

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 22, 2026