Bowel Preparation, Colonoscopy, Predictive Model
Conditions
Keywords
factors, bowel preparation, colonoscopy
Brief summary
The rate of adequate bowel preparation is one of important quality indicators of colonoscopy. Inadequate bowel preparation negatively affects the outcomes of colonoscopy. If patients with inadequate bowel preparation were identified before the procedure, enhanced strategy could be offered to achieve better bowel cleaning. Currently, there were three predicting models of inadequate bowel preparation established based on patient-related factors. So far, none of predictive models have been tested in other than their validation cohort populations, and no study has attempted to apply a different regimen to patients presenting with risk factors for inadequate colon cleanliness. In previous studies, we established a prediction model based on procedure-related factors, which has better accuracy and can better predict the quality of bowel preparation. The aim of this study is to compare the quality of bowel preparation by using a predictive model based on procedure-related factors versus the criterion group in unsedation patients
Interventions
DRUGPolyethylene glycol
Before colonoscopy, patient-related and procedure-related parameters were collected by one investigator in each center. In MI group, a procedure-based score, used for predicting inadequate bowel preparation, was calculated for each patients. Patients with score ≥3 were asked to taking another dose of PEG (1.5L) within 1-2 hours. Colonoscopy was performed in afternoon (about 4h after drinking PEG). Patients with score\<3 in IM group and those in the control group underwent colonoscopy directly
Sponsors
Air Force Military Medical University, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Age: 18\ 75 years * Patients undergoing morning colonoscopy
Exclusion criteria
* colon resection; * suspected bowel obstruction; * moderate or severe complications related to drinking the 1st or 2rd dose of PEG * hemodynamically unstable; * lactating or pregnant women; * no need to reach the ileocecal segment * unwilling to provided informed content.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adequate bowel preparation | 6 months | Defined by each segmental BBPS≥2 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adenoma detection rate | 6 months | The proportion of participants with at least one adenoma in each group |
| Overall complication related to bowel preparation | 6 months | — |
Countries
China
Outcome results
None listed