Open Versus Laparoscopic Right Hemicolectomy for Right Colon Cancer

Open Versus Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision and Central Vascular Ligation for Right Colon Cancer. A Randomized Prospective Study.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04434508

Acronym

CME

Enrollment

Registered

2020-06-17

Start date

2017-07-01

Completion date

2020-01-25

Last updated

2020-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic Cancer

Keywords

Colonic Cancer, laparoscopic right hemicolectomy, complete mesocolic excision

Brief summary

The aim of this study is to demonstrate the feasibility, surgical, and oncologic outcomes of laparoscopic right hemicolectomy with CME and CVL compared to open surgery.

Detailed description

The aim of this study is to demonstrate the feasibility, surgical, and oncologic outcomes of laparoscopic right hemicolectomy with CME and CVL compared to open surgery. Enrolled patients in the study were randomized to either laparoscopic or open right hemicolectomy with CME and central vascular ligation. The randomization process was performed using a closed envelope method which was withdrawn in the outpatient clinic by a nurse. The primary outcome was the number of lymph nodes (LNs) harvested among both groups. Secondary outcomes included operative time, blood loss, postoperative complications, and hospital stay.

Interventions

PROCEDURElaparoscopic right hemicolectomy with CME and central v

laparoscopic right hemicolectomy with CME and central v

PROCEDUREOpen right hemicolectomy with CME and central v

Open right hemicolectomy with CME and central v

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Masking description

Enrolled patients in the study were randomized to either laparoscopic or open right hemicolectomy with CME and central vascular ligation. The randomization process was performed using a closed envelope method which was withdrawn in the outpatient clinic by a nurse.

Intervention model description

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients with right colonic cancer

Exclusion criteria

* Patients with distant metastasis, large tumors with extra-colonic invasion emergency presentation (bowel obstruction or perforation)

Design outcomes

Primary

Measure	Time frame	Description
the number of lymph nodes (LNs) harvested among both groups	30 DAYS	the number of lymph nodes (LNs) harvested among both groups

Secondary

Measure	Time frame	Description
operative time	INTRAOPERATIVE	operative time
blood loss,	intraoperative	blood loss,
post-operative complications	30 days	post-operative complications

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026