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Early PONV - a Registry Based Study in Sweden.

Risk of Early Postoperative Nausea and Vomiting (PONV) - a Study With Data From the Swedish Perioperative Register (SPOR).

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04433676
Acronym
SPOR-PONV
Enrollment
1500000
Registered
2020-06-16
Start date
2016-01-01
Completion date
2029-12-31
Last updated
2026-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Complications, Postoperative Nausea and Vomiting

Brief summary

The study is an registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV). The study will explore several cohorts (for example a specific procedure) on a national basis, report the risk for early PONV and identify associated factors.

Detailed description

The study is a registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV). Almost all hospitals in Sweden report surgical procedures to SPOR and for the years 2016-2019 there are almost 1.7 million procedures in the registry for patients \>18years. Data will be extracted from SPOR on a yearly basis and results will be reported on selected cohorts (time periods and/or type of surgical procedure) during the study period. There is an option for hospitals to register nausea and vomiting occurring at the recovery unit and submit the data to SPOR. If a hospital choose to use the variable in their dataset, all patients at their unit needs to be registered either with \[No\_Nausea or Vomiting\], \[Nausea\] or \[Nausea or Vomiting\]. In the year 2019, more than 50% of procedures under anesthesia in the registry had registration of PONV. The strength with this system is that if a unit uses the variable, all cases will be classified either as "noPONV" or "PONV". The investigators aim to use the variable PONV at the recovery unit to describe the risk for early PONV and explore associated factors in several cohorts of surgical procedures in Sweden. The first dataset (2016-2018) was sent to the investigators from the SPOR registry in May 2019 and during the period June 2019- May 2020, the dataset was used to build up a model for the analysis of data with a preliminary report of elective surgeries in Sweden the year 2017. An updated dataset (all cases 2016-2025) was retrieved from SPOR in June 2026 and further analysis and reporting is based on the most updated dataset (yearly basis until 2029).

Interventions

OTHERno intervention

Sponsors

Jakob Wallden
Lead SponsorOTHER_GOV
Umeå University
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Procedure under general or regional anaesthesia * Age \>=18 years at the day of the procedure.

Exclusion criteria

* No entry of the PONV-variable in the SPOR-registry

Design outcomes

Primary

MeasureTime frameDescription
PONVAt the recovery unit, up to 24 hours after surgery.Nausea or Vomiting

Countries

Sweden

Contacts

CONTACTJakob Wallden, MD PhD
jakob.wallden@umu.se0046703644392
PRINCIPAL_INVESTIGATORJakob Wallden, MD PhD

Region Västernorrland (Västernorrland County Council)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 20, 2026