Cerebrovascular Disorders, Cognitive Impairment, Hemodialysis
Conditions
Brief summary
In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.
Interventions
None listed
Sponsors
Huashan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. maintenance hemodialysis patients who are younger than 85 years old and older than 50 years old, regardless of gender 2. dialysis vintage is greater than 3 months;
Exclusion criteria
1. Those with severe infection and anemia (Hb \<60g / L); 2. Those with severe mental illness, metabolic diseases and immune system diseases; 3. Patients with abnormal liver function
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cerebrovascular disease | 5 years | Magnetic resonance images will be used to determine the severity of white matter hyperintensity, using the Scheltens scale. Score 2 or more is abnormal. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| changes in cognitive function | 5 years | The Mini-Mental State Examination (MMSE) will be used to assess the changes in cognitive function.The MMSE has a maximum score of 30 points. The scores are generally grouped as follows: 25-30 points: normal cognition 21-24 points: mild dementia 10-20 points: moderate dementia 9 points or lower: severe dementiaThe Mini-Mental State Examination (MMSE) will be used to assess the changes in cognitive function.The MMSE has a maximum score of 30 points. The scores are generally grouped as follows: 25-30 points: normal cognition 21-24 points: mild dementia 10-20 points: moderate dementia 9 points or lower: severe dementia |
Countries
China
Contacts
Primary ContactJing Chen
Outcome results
None listed