Anaesthesia and Apoptosis

Effect of Anaesthesia on Apoptosis During Congenital Heart

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04431505

Enrollment

Registered

2020-06-16

Start date

2020-06-12

Completion date

2020-12-11

Last updated

2020-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apoptosis

Brief summary

Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo

Interventions

OTHERapoptosis

study of apoptotic changes due to anaesthesia

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to 10 Years

Inclusion criteria

* congenital heart corrective surgery

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame	Description
apoptotis during anaesthesia	24 hours	measuring markers of apoptosis pathway

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026