Does Delaying Curative Surgery for Colorectal Cancer Influence Long-term Disease Free Survival.

Does Delaying Curative Surgery for Colorectal Cancer Influence Long-term Disease Free Survival.: A COHORT STUDY

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04430231

Enrollment

602

Registered

2020-06-12

Start date

2012-01-01

Completion date

2020-04-01

Last updated

2020-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Brief summary

This work is an original clinical research article describing the relationship between wait list tome for colorectal cancer patients and long-term survival. These findings are particularly relevant for management of surgical wait lists during crisis such as the Covid-19 pandemic. The lack of a relationship between wait list time and disease free survival and tendency for improved survival in the 4-6 week imply some colorectal cancer operations can be safely delayed during times of limited resources.

Detailed description

Background Surgical wait list time is a major problem in many health-care systems and its influence on survival is unclear. The aim of this study is to assess the impact of the wait list time on long term disease-free survival in patients scheduled for colorectal cancer resection. Materials and Methods A prospective, single center study was carried out in patients with stage I-III colorectal cancer scheduled for surgery between 2012-2017 at a Colorectal Surgery Unit of a tertiary care center. Wait list time was defined as the time from completion of diagnostic workup and definitive surgery and divided into 2-week intervals from 2 to 6 weeks. The outcome variables were 2- and 5-year disease free survival. Screening for disease progression was with carcinoembryonic antigen levels and chest/abdominal computed tomography scan. Data was collected prospectively and subsequently analyzed.

Interventions

OTHERWait list time

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Inclusion criteria

* American Joint Committee on Cancer (AJCC) stage I through III confirmed adenocarcinomas * With colon or upper rectum as their primary site of malignancy according to International Classification of Diseases for Oncology, Third Edition topography code.

Exclusion criteria

* Emergency surgery, * More than one primary site, * Synchronous metastasis or peritoneal carcinomatosis at the time of surgery * If they received neoadjuvant chemoradiotherapy * If they had a local transanal excision.

Design outcomes

Primary

Measure	Time frame
Disease-free overall survival	5 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026