Cancer Breast, Chronic Pain Syndrome
Conditions
Keywords
serratus anterior plane block, magnesium sulphate
Brief summary
Modified radical mastectomy may be associated with severe post-operative pain, leading to chronic pain syndrome which usually requires optimal perioperative pain management.
Detailed description
Patients will be randomly into two equal groups (40 patients each) according to the adjuvant added to the local anesthetic (bupivacaine) in the serratus anterior plane block using a computer-generated random numbers concealed in sealed opaque envelopes. Group B: The patients will receive 20 ml of 0.5% bupivacaine plus 5 ml 0.9% normal saline with total volume 25 ml. Group BM: The patients will receive 20 ml of 0.5% bupivacaine plus 150 mg magnesium sulphate in 0.9% normal saline with a total volume of 25 ml.
Interventions
assess the pain intensity of magnesium sulphate as an adjuvant to bupivacaine in serratus anterior plane block for modified radical mastectomy
assess the pain intensity of magnesium sulphate as an adjuvant to bupivacaine in serratus anterior plane block for modified radical mastectomy
Sponsors
Study design
Eligibility
Inclusion criteria
* adult female patients * American Society Of Anesthesiologists (ASA) class I or II * scheduled for elective unilateral modified radical mastectomy
Exclusion criteria
* patient refusal * bilateral breast surgery * coagulation disorders * body mass index\> 35 * allergy to local anaesthetics or magnesium sulphate * severe respiratory or cardiac disorders * pre-existing neurological deficits * liver or renal insufficiency
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assessment of the pain intensity | 24 hours | Pain assessment by visual analogue scale |
Countries
Egypt