A Comparative Study of Mammography and Ultrasound for Breast Cancer Screening and Early Diagnosis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04429269

Acronym

MUSD

Enrollment

6000

Registered

2020-06-12

Start date

2020-06-12

Completion date

2023-06-01

Last updated

2020-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer Diagnosis, Breast Cancer Screening

Keywords

Mammography, ultrasound, breast cancer screening, early diagnosis

Brief summary

Improving the early diagnosis of breast cancer can reduce mortality. With mammography as the main tool for screening early breast cancer, the characteristics of dense breast and young onset of disease in Chinese women lowers the efficiency. The aim of this prospective study was to compare which method, x-ray or ultrasound, is more appropriate for screening and early diagnosis of breast cancer in Chinese women.

Detailed description

Breast cancer has become the most common malignancy in women. Improving the early diagnosis of breast cancer can reduce mortality. Mammography is recommended as the main tool for screening and early diagnosis of breast cancer in the guidelines of European and American countries. However, the characteristics of dense breast and young onset of disease in Chinese women make the screening and early diagnosis strategies of Western countries, which are mainly based on mammography, unsuitable for Chinese women. The aim of this prospective study was to compare which method, x-ray or ultrasound, is more appropriate for screening and early diagnosis of breast cancer in Chinese women.

Interventions

DIAGNOSTIC_TESTmammography and ultrasound screening

Patients screened by both mammography and ultrasound.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

35 Years to 70 Years

Inclusion criteria

* Informed consent, subjects 35-70 years old, asymptomatic, able to undergo ultrasound and x-ray

Exclusion criteria

* Localized breast erythema and ulceration, pregnancy, lactation, after previous breast implantation, already pathologically definite breast cancer patients

Design outcomes

Primary

Measure	Time frame	Description
screening yield	3 years	The sensitivity, specificity, positive predictive value, and negative predictive value of the screening methods.

Secondary

Measure	Time frame	Description
cost-effectiveness	3 years	The cost-effectiveness of each screening modality to detect one case of breast cancer

Countries

China

Contacts

Primary ContactSongjie Shen, MD

shensj@pumch.cn(010) 6915 8721

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026