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Prosthetic Valve and Graft Endocarditis With Mycobacterium Chimaera

Prosthetic Valve and Graft Endocarditis With Mycobacterium Chimaera: Diagnosis, Course of Disease, and Therapy Recommendations

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04429256
Enrollment
7
Registered
2020-06-12
Start date
2020-04-10
Completion date
2022-12-31
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mycobacterium Chimaera Infections

Keywords

cardiac bypass heater-cooler devices, cardiac surgery

Brief summary

Mycobacterium chimaera infections have occurred in post-cardiac surgery patients in association with contaminated cardiac bypass heater-cooler devices. So far optimal therapeutical concepts are not clear. At the University Hospital Basel Mycobacterium chimaera- infected protheses are replaced to decrease pathogenic burden and to support antibiotic long- term treatment. This study is to analyze the efficacy of this therapeutic approach.

Interventions

OTHERdata collection

retrospective analysis of perioperative data collected from patient medical charts and from a telephone enquiry

Sponsors

University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with Mycobacterium chimaera infections after cardiac surgery at University Hospital Basel

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
summary of disease course in patients with Mycobacterium chimaera- infections after cardiac surgeryat baselineDescriptive statistical analysis of disease course in patients with Mycobacterium chimaera- infections after cardiac surgery
summary of therapeutic interventions in patients with Mycobacterium chimaera- infections after cardiac surgeryat baselineDescriptive statistical analysis of therapeutic interventions in patients with Mycobacterium chimaera- infections after cardiac surgery

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026