Arterial Disease, Inguinal Hernia
Conditions
Keywords
Inguinal Hernia, Arterial Disease, Peripheral artery disease, Carotid stenosis, Arterial aneurysm
Brief summary
Inguinal hernias are associated with problems related to the venous system by the linking to extracellular matrix alterations (ECM). On the other hand, arterial diseases (arterial aneurysms, carotid, stenosis, peripheral artery disease) are widespread in the general population and may share others pathological pathways related to ECM impairment. Aim to this study is to evaluate the prevalence of arterial diseases in patients with inguinal hernia.
Detailed description
Previous studies showed the correlation between inguinal hernias and venous disease. The common pathophysiological pathway between these clinical conditions is linked to extracellular matrix (ECM) alterations. Arterial diseases, mainly represented by carotid stenosis, peripheral artery disease and arterial aneurysms, are widespread in western population and are responsible of high rates of morbidity and mortality. These diseases are also related to some ECM alterations. Aim of this cross-sectional study is to evaluate the prevalence of arterial disease among patients with inguinal hernias. The primary endpoint of this study is to provide new epidemiological evidences on this association that may help physicians in novel preventive strategies. The study will consider the inclusion of consecutive patients assessed for inguinal hernia over 1 year period in order to study the prevalence of concomitant arterial disease, by means of office visit, echo duplex scan of the aorta and its main branches, carotid arteries and lower limb arteries.
Interventions
DIAGNOSTIC_TESTIn-office vascular visit
Every patient will undergo a complete physical examination in order to detect any clinical or sub clinical vascular disease.
DIAGNOSTIC_TESTEcho duplex scan of arterial system
Every patient will undergo a complete echo duplex scan in order to detect any morphological or hemodynamic alteration of aorta, carotid arteries and lower limb arteries.
Sponsors
University of Catanzaro
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* patients with inguinal hernia
Exclusion criteria
* patients with malignancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of arterial disease in patients with inguinal hernia | at 1 year | Patients with inguinal hernia will be assessed for the presence of arterial aneurysm, carotid stenosis, and peripheral artery disease in order to find any correlation between these pathological conditions. |
Countries
Italy
Contacts
Primary ContactRaffaele Serra, M.D., Ph.D.
Outcome results
None listed