Electrophysiology in Congenital Cataract After Lensectomy and Anterior

The Change of Electrophysiology in Congenital Cataract After Lensectomy and Anterior Vitrectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04427748

Enrollment

116

Registered

2020-06-11

Start date

2018-01-01

Completion date

2019-12-03

Last updated

2020-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Cataract

Keywords

ERG

Brief summary

In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test group, 25 normal eyes as control group. The a- and b-wave and PhNR related parameters was evaluated.

Detailed description

Secondary IOL implantation in aphika children and lensectomy and anterior vitrectomy and primary IOL implantation in children with congenital cataract were both performed by the same surgeon(Z.Y.E). electroretinography and photopic negative response are performed to each patient.The research was to evaluate the relationship between the best corrected visionn and the related parameters of a- and b-wave and PhNR .

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Months to 15 Years

Healthy volunteers

Yes

Inclusion criteria

* phakic children diagnosed with congenital cataract who underwent secondary IOL implantation and children with congenital cataract who underwent lensectomy and anterior vitrectomy and primary IOL implantation

Exclusion criteria

* patients with mild cataracts do not require surgery

Design outcomes

Primary

Measure	Time frame	Description
ERG	at least 1year after the surgery of congenital cataract	investigate retinal function changes of congenital cataract children. ERG related parameters including a- and b-wave and PhNR amplitude and latency.

Countries

China

Outcome results