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Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracic Surgery

Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracoscopic Surgery

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04426097
Enrollment
40
Registered
2020-06-11
Start date
2020-07-01
Completion date
2022-07-01
Last updated
2020-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Video-assisted Thoracoscopic Surgery

Keywords

vagus nerve block

Brief summary

Currently, there is a trend toward non-intubated anesthesia methods for video-assisted thoracic surgery in our hospital. During the surgery, intrathoracic vagus nerve blockade is suggested for inhibit cough reflex in previous paper. However, right and left side of vagus nerves both deep near the aorta or trachea respectively. To achieving the procedure may induce cough reflex by lobar traction even result vital organ damage. This study aims to apply alternative vagus nerve blockade at neck level via ultrasound guidance and test if the procedure real reduce cough reflex then previous method. We also follow up the patient's vital sign, vocal cord and diaphragm movement, horner syndrome and hoarseness to evaluating if cervical vagal blockade has the potential risk involve other surrounding nerves

Interventions

PROCEDURECervical Vagal Blockade

Cervical Vagal Blockade with 0.5 % ropivacaine 2.5 ml and 2% xylocaine 2.5 ml

PROCEDUREWithout Blockade

Without Blockade

Sponsors

Taipei Medical University WanFang Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 79 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults younger than 80 years old are scheduled for one-port video assisted thoracic surgery

Exclusion criteria

* Anticipated difficult airway, Respiratory insufficiency,Vocal cord palsy,diaphragm palsy parkinsonism,previous stroke,tachycardia

Design outcomes

Primary

MeasureTime frameDescription
Effect of Cervical Vagal Blockade on Cough IncidenceDuring the VATS procedurenumber of coughing episodes

Contacts

Primary ContactLin Jui An, PhD
greenscatter1031@gmail.com+886-66382736,

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026