Type 2 Diabetes
Conditions
Brief summary
The study will assess the serum expression of MMP-9 in normal people, type 2 diabetic patients and type 2 diabetic patients with atherosclerosis.
Interventions
DIAGNOSTIC_TESTdiagnosed as type 2 diabetes without atherosclerosis
patients diagnosed as type 2 diabetes without atherosclerosis
DIAGNOSTIC_TESTdiagnosed as type 2 diabetes with atherosclerosis
patients diagnosed as type 2 diabetes with atherosclerosis
DIAGNOSTIC_TESTpeople without type 2 diabetes or atherosclerosis
normal people without type 2 diabetes or atherosclerosis
Sponsors
Majianhua
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* volunteer to participate and be able to sign informed consent prior to the trial. * patients with type 2 diabetes, aged 18-60 years old, meeting WHO1999 diagnostic criteria, have not used any drugs. * The patients have completed carotid ultrasound during hospitalization.
Exclusion criteria
* patients with any antidiabetic drugs. * impaired liver and kidney function with ALT 2.5 times higher than the upper limit of normal value; Serum creatinine was 1.3 times higher than the upper limit of normal. * drug abuse and alcohol dependence in the past 5 years. * systemic hormone therapy was used in the last three months. * patients with infection and stress within 4 weeks. * any other obvious conditions or associated diseases determined by the researcher: such as severe cardiopulmonary diseases, endocrine diseases, neurological diseases, tumors and other diseases, other pancreatic diseases, history of mental diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total MMP-9 levels | 6 months | the different group of total MMP-9 levels |
Countries
China
Contacts
Primary ContactJianhua Ma, Doctor
Outcome results
None listed