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Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection.

Possibilities of Chest Magnetic Resonance Imaging (MRI) in Diagnostics of COVID-19. The Use of MRI to Assess Lung Damage in Patients With Coronavirus Infection

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04424355
Enrollment
25
Registered
2020-06-09
Start date
2020-05-19
Completion date
2021-12-20
Last updated
2023-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus Infections, Pneumonia

Keywords

Computed tomography, Magnetic resonance imaging, Lung MRI

Brief summary

Since the onset of the COVID-19 pandemic, the importance of chest computed tomography (CT) in detecting signs of viral pneumonia has become clear from the literature. However, the increased patient flow creates an additional pressure on CT centers. We believe, the use of chest magnetic resonance imaging (MRI) can help to test patients for CОVID-19 when CT scan is not available. Lung MRI may be useful in routing a patient in a difficult epidemiological situation.

Detailed description

Currently, with increased load of CT studies, alternative methods of viral pneumonia signs' visualization are required. Investigators hypothesize that chest MRI could be a test for detecting pulmonary features of COVID-19. They consider using MRI to assess COVID-19 viral pneumonia. Absence of radiation exposure to patients is a clear advantage of MRI. This is a prospective, observational cohort study assessing patients with suspected COVID-19. It's primary goal is to determine the ability of multiparametric MRI to detect lung abnormalities - ground-glass opacity (GGO), consolidation, crazy paving pattern, pleuritis - in comparison to CT scan. In this study each patient with suspected pneumonia will sequentially undergo both chest CT and MRI during his/her visit. Scan protocols will be identical for each patient. Each participants completed an online questionnaire.

Interventions

DIAGNOSTIC_TESTChest MRI

Patients referred by the primary care physician with suspected pneumonia

Sponsors

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* A referral from the attending physician for a chest CT scan * Suspected pneumonia * Signed informed consent * Over 18 years old

Exclusion criteria

* Pregnant or nursing women * Presence of foreign implanted objects in the body at the scan level (including cardiac pacemakers, spine metalware)

Design outcomes

Primary

MeasureTime frameDescription
Number of zones of pulmonary parenchyma corresponding to viral pneumonia detected by chest MRI in comparison with CT scanUpon completion, up to 1 yearExpected number - more than two zones

Countries

Russia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026