Remineralization Efficacy of Gum Arabic Varnish.

Remineralization Efficacy of Gum Arabic Varnish Versus Fluoride Varnish and CPP-ACP With Fluoride Based Varnish on Initial Carious Lesions. a Randomized Controlled Clinical Trial.

Status

UNKNOWN

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04422860

Enrollment

Registered

2020-06-09

Start date

2020-10-31

Completion date

2021-11-30

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries,Dental, Remineralization, White Spot Lesion

Keywords

Initial carious lesion, Gum Arabic, Remineralization power, fluoride varnish, Mi varnish, Acacia senegal

Brief summary

The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.

Interventions

DRUGGum Arabic varnish

Powdered exudate from various Acacia species, especially A. senegal (Leguminosae).

DRUGProflourid Varnish,VOCO

5% NaF varnish

DRUGMI Varnish,GC Japan Inc.

CPP-ACP with fluoride based varnish

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

17 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients with initial carious lesions. * Proper Oral hygiene.

Exclusion criteria

* Patients with a compromised medical history. * Patients with active severe periodontal disease. * Patients with hypoplastic or hypomineralized teeth.

Design outcomes

Primary

Measure	Time frame	Description
Remineralization through determination of lesion progression or regression	Change from baseline at 3,6, 9 months	Determination of lesion level by DIAGNOdent which provides a laser fluorescence feedback to give a numerical readout reflects the amount of demineraliztion.

Secondary

Measure	Time frame	Description
Caries lesion activity assessment	Change from baseline at 3,6, 9 months	Visual (change in Surface Appearance) - tactile ( change in Tactile Feeling of the surface by an explorer)

Countries

Egypt

Contacts

Primary ContactRawda H. A.ElAziz, Post Phd

rawda.hesham@dentistry.cu.edu.eg00201001097200

Backup ContactAhmed H. Samaha, BSc

Ahmed.hesham@dentistry.cu.edu.eg

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026