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Correlation Between HRV and Performance in Eccentric Resistance Training Associated With Partial Blood Flow Restriction

Correlation Between Heart Rate Variability and Performance in Eccentric Resistance Training Associated With Partial Blood Flow Restriction: a Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04422301
Enrollment
60
Registered
2020-06-09
Start date
2021-05-18
Completion date
2021-06-18
Last updated
2021-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Keywords

resistance training, vascular occlusion, performance, autonomic nervous system, recovery of physiological function

Brief summary

Studies on resistance training (RT) associated with blood flow restriction (BFR) is an alternative method of gaining strength and hypertrophy muscle. However, there is a gap correlated to autonomic repercussion of BFR and performance. Thus, it becomes relevant to investigate this type of training in post-exercise. Objective: investigate and compare autonomic and performance responses of 6 weeks of eccentric RT with different intensities associated or not to BFR in healthy youngsters. Method: This is a randomized clinical trial including 60 healthy men aged 18-35 years, divided into four groups according to exercise intensity and BFR: 80% without BFR, 40% without BFR, 80% with BFR and 40% with BFR. Exercise intensity will be determined by the peak of excentric torque on the isokinetic dynamometry method and by the BFR, as being 40% of the intensity required for the complete examination of the blood flow evaluated by Doppler. Participants will do an eccentric femoral quadriceps muscle exercise session on the isokinetic dynamometer according to the previously randomized group. For recovery analyzes, it will be used: the root-mean-square of the successive normal sinus RR interval difference (rMSSD); high frequency (HF) ms²; HF(nu) and the standard deviation of instantaneous beat-to-beat interval variability (SD1). For performance, it will be used the single leg hop test. For data analysis of the population profile, the descriptive statistical method will be used and the results will be presented with values of means, standard deviations, median and confidence interval. Initially, participants from all study groups will be dichotomized at each performance outcome (muscle strength test on the isokinetic dynamometer and vertical jump test) as improvement or without improvement in order to demonstrate the behavior of the responses obtained during the training, that is, whether the individual responded to the RT or not. It is worth mentioning that this qualitative analysis will be performed considering the data obtained from the initial, intermediate and final evaluation. The dichotomization of the results of the functional tests will be performed by the typical error of the sample measurement for each test. It will be considered as improvement if the participant presents gains in tests above the typical error of the measure. The values obtained from the initial, intermediate and final evaluation will be analyzed independently. Subsequently, the weekly average of the vagal indices (rMSSD, HF and SD1) will be performed in the baseline moment and after 6 weeks of RT moment of each study group. In the sequence, the performance parameters will be correlated with the autonomic parameters in the respective groups. Pearson or Spearman correlation test will be used according to the normality of the data. The level of significance will be p \<0.05 for all tests. The statistical program SPSS (Statistical Package for the Social Sciences) will be used for the analyzes.

Interventions

OTHERBlood flow restriction

an alternative method to produce strength and muscle hypertrophy with lower intensities

Sponsors

Franciele Marques Vanderle
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* male sex; * healthy; * aged between 18 and 35 years

Exclusion criteria

* smokers * alcoholics; * use drugs that influenced cardiac autonomic activity; * cardiovascular, metabolic or endocrine diseases.

Design outcomes

Primary

MeasureTime frameDescription
PerformanceBaselineSingle Leg Hop Test
HRV - rMSSDduring the 6 weeks of trainingrMSSD (square root of the mean squared differences of successive N-N intervals)
HRV - SD1during the 6 weeks of trainingSD1 - the standard deviation of instantaneous beat-to-beat interval variability
HRV - HF (ms²)during the 6 weeks of trainingHF (ms²) - (high frequency)
HRV -HF (nu)during the 6 weeks of trainingHF (nu) - (high frequency)

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026