Anastomotic Leak
Conditions
Brief summary
Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application of scoring scale to assess presence or absence of leakage.
Interventions
DIAGNOSTIC_TESTPredictors of intestinal anastomosis leakage, application of new predictors and new scores
Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application of scoring scale to assess presence or absence of leakage.
Sponsors
Mansoura University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Any patient with intestinal or colonic anastomosis either elective or emergent.
Exclusion criteria
* Patients with inflammatory bowel disease will be excluded because this could influence plasma levels of inflammatory biomarkers. * patients using corticosteroids * Patients unfit for anaesthesia, those having collagen diseases or hematological disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Early detection and management of intestinal anastomotic leak | 6 months | Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leak(Intestinal fatty acid binding protein, Procalcitonin and CRP) with application of scoring scale(Dekker et al 2011) (Dulk et al ., 2013) to assess presence or absence of leakage. |
Countries
Egypt
Contacts
Primary ContactMohamed Arnouse
Outcome results
None listed