The Effect Of Preoperative Parameters On Success After DMEK Surgery

The Effect Of Preoperative Anterior Segment Parameters On Success After Descemet Membrane Endothelial Keratoplasty (Dmek) Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04420429

Enrollment

Registered

2020-06-09

Start date

2019-06-01

Completion date

2022-07-10

Last updated

2022-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angle's Classification, Descemet's Membrane; Defect, Endothelial Dysfunction, Fuchs' Endothelial Dystrophy, Herpetic Keratitis, Pseudophakic Bullous Keratopathy

Keywords

Descemet Membrane, anterior chamber depth, axial length, endothelial count, Descemet membrane endothelial keratoplasty

Brief summary

The aim of this study is to evaluate the effect of preoperative parameters on surgical results in Descemet Membrane Endothelial Keratoplasty (DMEK) surgery.

Detailed description

In patients undergoing Descemet Membrane Endothelial Keratoplasty (DMEK) surgery; preoperative anterior chamber depth, angle parameters, axial length and corneal parameters will be evaluated. The effects of these parameters on surgical results will be examined.

Interventions

PROCEDUREDescemet membrane endothelial keratoplasty (DMEK)

All participants underwent DMEK surgery

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Scheduled to undergo Descemet membrane endothelial keratoplasty(DMEK) * aged 18 old older

Exclusion criteria

* Patients with corneal pathology other than endothelial insufficiency * Glaucoma patients, * Patients who have previously had any keratoplasty procedure

Design outcomes

Primary

Measure	Time frame	Description
Change in endothelial cell density	after surgery 1, 3, 6, and 12 months	Change from baseline
Change in visual acuity	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline

Secondary

Measure	Time frame	Description
Change in maximum (steepest) and minimum (flattest) keratometry values in the central corneal zone	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline
Change in anterior chamber depth	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline
Change in central pachymetry	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline
Change in axial length	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline
Change in intraocular pressure	Baseline and after surgery 1, 3, 6, and 12 months	Change from baseline

Other

Measure	Time frame	Description
Surgical complications	During surgery	Complications occurring during the surgery will be recorded.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026