The Effect of Intravenous Tranexamic Acid and Interscalene Block Applied on Shoulder Arthroscopy

The Effect of Intravenous Tranexamic Acid and Interscalene Block Applied on Shoulder Arthroscopy on Total Blood Loss; a Prospective, Randomized, Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04419246

Enrollment

Registered

2020-06-05

Start date

2020-07-15

Completion date

2021-07-15

Last updated

2020-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nerve Block, Tranexamic Acid

Brief summary

Nerve blocks are used for pain and surgery after many operations today. It has been demonstrated by studies that the amount of postoperative bleeding decreases. On the other hand, surgical teams can use additional medications, such as Tranexamic acid, which have been proven by different studies that have reduced bleeding during and after arthroscopic surgery.

Detailed description

The investigators aimed to investigate the effect of interscalene block application and tranexamic acid on bleeding in shoulder arthroscopy operation.

Interventions

OTHERinterscalene block

ultrasound guided ultrasound guided interscalene block 30 minutes before operation. 30 minutes before operation.

DRUGtranexamic acid

10 mg/kg intravenous tranexamic acid 10 minutes before the incision.

OTHERgeneral anesthesia

general anesthesia will be applied in accordance with standard procedures

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Patients who were in the American Society of Anesthesiologists (ASA) I-III class * underwent elective shoulder arthroscopy * Patients with consent to participate in the study

Exclusion criteria

* history of arterial or venous thromboembolic disease * Bleeding diathesis disorder * Allergy to local anesthetics * cardiac stent placement

Design outcomes

Primary

Measure	Time frame	Description
serum hemoglobin exchange	preoperative, postoperative 1st and 2nd day	change of serum hemoglobin before and after operation

Secondary

Measure	Time frame	Description
postoperative bleeding amount	postoperative 24 hours	The volume of drainage
Visual Analog Scale	Postoperative 24 hours	Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0= no pain, 10=intolerable pain)

Contacts

Primary ContactKorgün Ökmen, Assoc. PhD.

korgunokmen@gmail.com+902242955000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026