Early Systolic Notching in Pulmonary Embolism

Diagnostic Accuracy of Early Systolic Notching in Pulmonary Embolism

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04413825

Enrollment

180

Registered

2020-06-04

Start date

2020-06-15

Completion date

2021-01-15

Last updated

2021-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism

Brief summary

Venous thromboembolism (VTE), clinically seen as deep vein thrombosis (DVT) or pulmonary embolism (PE), is the third most common acute cardiovascular syndrome after myocardial infarction and stroke. In a study conducted by critical care and emergency physicians, lung ultrasonography (US) for pleural infarction areas, lower extremity venous US in terms of DVT, and focused cardiac US in terms of right ventricular strain were demonstrated with different diagnostic values for PE. However, no ultrasonographic method alone has a high diagnostic value for PE alone in the literature. In a recent study, it is stated that a new cardiac finding (early systolic notch- ESN) has high sensitivity (92%) and specificity (99%) in massive and submassive emboli. However, the limited patient population and the exclusion of many patient groups limits the applicability of the study and its use in other patient groups. With this study, it was aimed to determine the diagnostic value of ESN finding within the emergency department conditions by keeping the patient population wider.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing pulmonary CT angiography with suspicion of pulmonary embolism

Exclusion criteria

* Pregnant women, * Patients under 18 years of age, * Those who received thrombolytic therapy, * Poor ultrasound imaging.

Design outcomes

Primary

Measure	Time frame	Description
To determine the diagnostic accuracy of the ESN finding	6 months	What is the diagnostic value of ESN finding in patients with PE diagnosed with pulmonary CT angio?

Countries

Turkey (Türkiye)

Outcome results