Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, Telerehabilitation, Supervised exercises, Structured exercise, Quality of Life, Activities of Daily Living
Brief summary
Multiple sclerosis (MS) is a complex neurodegenerative autoimmune disease. People with MS (PwMS) have low quality of life (QoL) and activities of daily living (ADL). Exercise is a safe and effective rehabilitation tool for PwMS. A structured and personalized exercise program can improve physical fitness, functional capacity, quality of life and modifiable disorders in PwMS. On the other hand, Telerehabilitation is an alternative rehabilitation method in PwMS. The purpose of this study is to investigate the effectiveness of exercise programs and telerehabilitation on ADL and QoL in PwMS, and compare the effects of supervised exercise and home-based exercise programs for the PwMS.
Detailed description
Participants are randomly assigned to the structured supervised exercise or structured home-based groups. Interventions in Group 1 (n=15) includes one session per day, 3 days a week over a 12-weeks structured exercise program under the supervision of a physical therapist. Group 2 (n=15) includes a 12-week structured home-based exercise program checked and controlled through telerehabilitation three times a week. All measurements pre-post intervention.
Interventions
BEHAVIORALStructured Supervised Exercise
Structured Exercise Program under the supervision of Physical Therapist
BEHAVIORALStructured telerehabilitation
Structured Exercise Program checked and controlled through telerehabilitation
Sponsors
Istanbul University - Cerrahpasa
Medipol University
Istanbul University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
Participants will randomly assign to the structured supervised exercise or structured home-based groups. Randomization are done using Microsoft Excel 'RAND()' function.
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
patients with: 1. Stable period at the time of application to the clinic 2. Expanded Disability Status Scale Levels between 2 - 6.5 3. Appropriate cognitive level to understand the exercises 4. No diseases to affect their participation in exercise programs
Exclusion criteria
patients with: 1. Poorly controlled diabetes, hypertension or other medical conditions to be incompatible with study participation, 2. A new history of previous attacks 3. No reliable informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional Independence Measure (FIM) | Changes after 12 weeks | FIM is a tool used for evaluation of primary ADL of people with disability. FIM items include self care, sphincter control, transfers, locomotion, communication, and social cognition subgroups. Grading is based on 7 points. 7: complete independence, 6: modified independence, 5, 4 and 3: modified dependence, 2 and 1: complete dependence. |
| Nottingham Health Profile, First section (NHP-I) | Changes after 12 weeks | NHP is a tool used for measuring and definition of QoL regarding the health status in general. NHP-I contains 38 yes/no statements, focusing on different aspects of the general health problems, including six dimensions of subjective health defined as physical abilities, pain, sleep, energy, emotional reaction, energy level and social isolation. Questions are evaluated according to the patients' yes/no responses and are scored between 0 and 100. High scores indicate high level health status in the specified item. Total scores are summed in all fields. |
| Quality of life scale (QoLS) | Changes after 12 weeks | QoLS is a standardized interview consisting of 41 questions clustered in four subscales: functional and economic scale, social and recreational scale, affect and life in general scale, and medical problems scale. Each question in the scale is evaluated over 5 points. (1 is negative at all times and 5 is the best response). |
Countries
Turkey (Türkiye)
Outcome results
None listed