Liver Cancer
Conditions
Keywords
RFA, liver cancer, surgical resection
Brief summary
In this retrospective study, the investigators assessed the application of radiofrequency-assisted liver resection in intractable liver cancer resection, and plan to analysis the different factors.
Detailed description
The primary clinical treatment of liver cancer is surgical resection, although many integrated applications develop rapidly, surgery is still the best way to remove the tumour lesion. Traditional ways that have curative removed tumours in three methods, which are liver resection, liver transplantation and radiofrequency ablation (RFA). As for primary liver cancer, surgery, and RFA are both effective and safety, but for the complexity of end-stage liver cancer, surgical resection may not remove the tumours alone. Surgical resection with radiofrequency ablation therapy for intractable liver cancer is a kind of active plan. The therapy can eliminate the tumour, maximize the protection of patient liver tissue, reduce operation damage, reduce the incidence of complications, and improve patients quality of life after surgery.
Interventions
PROCEDUREradiofrequency
radiofrequency combined with liver resection
PROCEDURETACE
only TACE treatment
PROCEDURETACE+radiofrequency
TACE followed by radiofrequency
Sponsors
Hepatopancreatobiliary Surgery Institute of Gansu Province
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Ultrasound-guided fine-needle aspiration pathology or postoperative pathology was confirmed to be liver cancer, no pathological results according to China 's 2017 version of the hepatocarcinoma (HCC) diagnosis and treatment specifications, in line with the standard clinical diagnosis of liver cancer * According to Barcelona Clinic Liver Cancer (BCLC) staging criteria, it is stage C (stage C: single tumour\> 5 cm or more than three tumours, and at least one tumour\> 3 cm, liver function Child-Pugh A or B, with lymph node metastasis or distant metastasis or portal vein or Venous liver trunk is invaded, penance Status (PST) score 1-2 points)
Exclusion criteria
* HCC patients with other malignant tumours * Metastatic liver tumour * Patients with liver abscess * Patients with organ dysfunction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The survival rates for one-year to five-year | 5 years | The survival rates was defined as the percentage of liver cancer for five years. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The hospital stay | 3 months | The length of stay in a hospital regarding days |
| The Child-Pugh score after therapy | 3 months | The Child-Pugh is based on the presence and severity of ascites and hepatic encephalopathy, the prolongation of prothrombin time, and the levels of serum bilirubin and albumin. According to the Child-Pugh scores, patients are classified into three classes (Child class A, B, and C with CP scores 5-6, 7-9, and 10-15, respectively) |
Countries
China
Outcome results
None listed