Intensive Care Unit Syndrome
Conditions
Keywords
Continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), Ionized hypomagnesemia, Monitoring of ionized magnesemia, Morbi-moratlity
Brief summary
It has been reported in several studies that ionized hypomagnesemia is associated with higher morbidity and mortality rates. During continuous renal replacement therapy with regional citrate anticoagulation (CRRT-RCA), the loss of magnesium has been reported to not be covered by magnesium concentration in ordinary dialysis fluid. This may lead to ionized hypomagnesemia. However the incidence of ionized hypomagnesemia in patients requiring CRRT-RCA remains unclear and need to be estimated to determine if ionized magnesium monitoring could be of interest. This study aim to assess the incidence of ionized hypomagnesemia induced by CRRT-RCA.
Interventions
None listed
Sponsors
Novamedica Laboratories
University Hospital, Montpellier
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Consecutive patients admitted to the ICU and requiring continuous renal replacement therapy with regional citrate anticoagulation * age \> 18 ans
Exclusion criteria
* Persons under protection * Paritcipation rejections
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assess the systemic ionized magnesemia change after 24h of CRRTsystemic variations of iMg | Day 0 and Day 1 | assess the systemic ionized magnesemia change after 24h of CRRT wiith regional citrate anticoagulation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of morbidity and mortality | 1 day | Assessment of morbidity and mortality |
| Proportion of patients with heart rhythm disturbances | 1 day | Proportion of patients with heart rhythm disturbances |
Countries
France
Outcome results
None listed