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COVID-19 Respiratory Distress and Antithrombotic Drugs in Subject's Habits

COVID-19 Respiratory Distress and Antithrombotic Drugs inSubject's Habits

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04412473
Acronym
CRASH
Enrollment
1000
Registered
2020-06-02
Start date
2020-04-30
Completion date
2021-06-30
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sars-CoV2

Keywords

Sars-CoV2, Covid-19, Antithrombotic treatments, ARDS, Hypoxemia, Thrombosis, Pulmonary arteries, Endothelial

Brief summary

Current management of VID-19 consists of oxygen support without specific treatment. Hospitalization may suddenly require delayed resuscitation. This evolution corresponds to an atypical acute respiratory distress syndrome (ARDS), the mechanism of which is poorly understood and difficult to predict. The general pathophysiology of ARDS, the vascular tropism of SARS-Cov2, the description of coagulopathy and numerous pulmonary artery thromboses in resuscitation and the encouraging investigation of antithrombotics in general ARDS

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Major Subject (≥18 years) * Subject hospitalised in HUS or GHRMSA for COVID-19 * The diagnosis COVID-19 confirmed by smear or evoked by CT scan or chest X-ray without a differential diagnosis retained in the medical record * Subjects who, after being informed, do not wish to have their data reused for the purposes of this research

Exclusion criteria

* Subject who expressed opposition to participating in the study * Subject under guardianship or trusteeship * Subject under safeguard of justice * Patient hospitalized in a geriatric service or in a ward not labeled COVID (surgery, oncology,...) or in a short-term hospitalization unit without transfer to another service. * Serious patient on admission to the emergency room and recused from resuscitation.

Design outcomes

Primary

MeasureTime frame
Analysis of Respiratory Distress and Antithrombolytic Therapy in Patients with covid191 month

Countries

France

Contacts

Primary ContactVincent CASTELAIN, MD, PhD
Vincent.CASTELAIN@chru-strasbourg.fr33 3 88 12 82 69
Backup ContactSaïd CHAYER, PhD, HDR
said.chayer@chru-strasbourg.fr33 3 88 11 66 90

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026