Bariatric Surgery, Micronutrient Deficiencies, Obesity
Conditions
Keywords
Bariatric Surgery (Gastric Bypass, Gastric Sleeve), Micronutrient Deficiencies, Adherence, Medication
Brief summary
The aim of this study is to assess medication adherence to vitamin and mineral supplements after bariatric surgery and identify factors that may influence adherence. All study participants are prescribed life-long treatment with daily oral vitamin B12 and Calcium/Vitamin-D. Menstruating women are also prescribed daily oral iron supplementation. Post-operative adherence rate is retrieved from Pharmacy refill data, collected from the Swedish Prescribed Drug Register, the five first years after bariatric surgery.
Detailed description
The aim of this study is to assess medication adherence to vitamin- and mineral supplementation after bariatric surgery, identify factors that may influence adherence, as well as study the development of micronutrient deficinencies detectable by blood sampling. All study participants are prescribed life-long treatment with daily oral vitamin B12 and Calcium/Vitamin-D. Menstruating women are also prescribed daily oral iron supplementation. Post-operative adherence rate is retrieved from pharmacy refill data, collected from The Swedish Prescribed Drug Register, at one, two and five years after bariatric surgery.
Interventions
PROCEDUREGastric Bypass, Sleeve Gastrectomy
Lifelong vitamin and Mineral supplementation
Sponsors
Region Östergötland
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Informed consent * Patients subjected to bariatric surgery at Vrinnevi Hospital, Norrköping, Sweden
Exclusion criteria
* Unable to read and understand Swedish
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adherence to vitamin and mineral supplementation | 5 years | Implementation (Continuous multiple-interval measures of medication availability/gaps, CMA), |
| Time to initiation | 1 year | Initiation (time to initiation) |
| Time to discontinuation | 5 years | Discontinuation (Time to discontinuation) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| s-folate | 5 years | nmol/L |
| p-calcium | 5 years | mmol/L |
| Self reported Adherence to vitamin-and mineral supplementation | 5 years | Medication Adherence Report Scale (MARS-5) score 1-25, higher scores mean a better outcome |
| s-cobolamin | 5 years | pmol/L |
| s-albumin | 5 years | g/L |
| Hemoglobin (Hb) | 5 years | g/L |
| Iron status | 5 years | µmol/L |
Countries
Sweden
Outcome results
None listed