Diabete Mellitus, Aging, Cognitive Change
Conditions
Brief summary
Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes. The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on clinical variables in older adults with type 2 diabetes.
Interventions
BEHAVIORALSitting
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
BEHAVIORALStatic standing
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
BEHAVIORALDynamic standing
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification. To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing. Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
Sponsors
University of Michigan
Science and Research Centre Koper
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* older participants (65+ years) with clinically confirmed type 2 diabetes * Body mass index above 25 and less than 40 kg/m2
Exclusion criteria
* participants unable to perform a short clinical and motor function test battery (sABC test, Mini-BEST)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen consumption | change in oxygen consumption between all three conditions, which will be measured with a minimum washout period of 3 days | Oxygen uptake VO2 (ml/min/kg) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Executive control | change in executive control and cognitive switching levels between all three conditions, which will be measured with a minimum washout period of 3 days | Executive functions measured with Trail Making Test (seconds) |
| Attention levels | change in attentional levels between all three conditions, which will be measured with a minimum washout period of 3 days | Measuring attention with Stroop test (seconds) |
Countries
United States
Contacts
Primary ContactNicolaas Bohnen, MD, PhD
Outcome results
None listed