Diabete Mellitus, Pancreatectomy; Hyperglycemia
Conditions
Keywords
Pancreatectomy, Diabetes Mellitus, pancreaticoduodenectomy
Brief summary
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
Detailed description
Biochemical markers of glucose metabolism including oral glucose tolerance tests, fasting blood glucose, insulin, glucagon and HbA1c were performed on patients receiving pancreatectomy (pancreaticoduodenectomy and distal pancreatectomy). Tests were done preoperatively, postoperatively at 3 months, and at 1 year. The primary endpoints were the incidence and risk factors of new-onset and worsened DM after each type of pancreatectomy.
Interventions
DIAGNOSTIC_TESToral glucose tolerance test
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* partial pancreatectomy
Exclusion criteria
* total pancreatectomy * incomplete testing * follow-up loss * death within 1 year
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence & risk factors of new-onset DM | at 1 year | incidence & risk factors of new onset DM after pancreatectomy |
| incidence & risk factors of worsened DM | at 1 year | incidence & risk factors of worsened DM after pancreatectomy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| characteristics of new-onset and worsened DM | 1 year | changes of glucose metabolism during study period |
Outcome results
None listed