Stress Hyperglycemia
Conditions
Brief summary
Whereas diabetes mellitus is clearly a risk factor for the occurrence of stroke and for its poor prognosis, hyperglycemia per se is also linked to increased morbidity and mortality in stroke patients.Therefore, the objective of this work was to study the glycemic status of acute ischemic stroke patients and to assess its impact on stroke outcome.
Detailed description
Using PASS program, setting alpha error at 5% and power of 80%, the total sample size was estimated to be 80 cases. The NIHSS was used as a primary outcome; 40 cases were needed in each group. Secondary outcomes were hemorrhagic transformation, hospital stay duration, mechanical ventilation, need for vasopressors, and 30-days mortality.
Interventions
OTHERstandard protocol for stroke patients
Standard protocol for stroke patients
Sponsors
Ain Shams University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Acute ischemic stroke within 24 hours of onset of symptoms
Exclusion criteria
* subdural hematoma * Transient ischemic attack * Subarachnoid hemorrhage * Hemorrhagic stroke * Major comorbidities Hyperglycemia on admission that was controlled (random blood sugar (RBS) \< 150 mg/dl) within 24 hours with insulin therapy, diabetic * Ketoacidosis * RBS less than 70 mg/dl on admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| National Institutes of Health Stroke Scale (NIHSS) | 30 days | The NIHSS score categorized into: no stroke symptoms (0), mild stroke (1-4), moderate stroke (5-15), moderate to severe stroke (16-20), and sever (21-42) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 30-days mortality | 30 days | Hemorrhagic transformation, the length of hospital stay, need for mechanical ventilation and vasopressors and 30-days mortality |
Countries
Egypt
Outcome results
None listed