Multiple Sclerosis, Traumatic Brain Injury
Conditions
Keywords
Processing Speed, Intervention, Multiple Sclerosis, Traumatic Brain Injury, Cognition
Brief summary
This study will examine the efficacy of a clinical intervention for improving emotional processing in individuals with MS and TBI.(1)The main outcome measure will be changes in emotional processing measures from pre to post treatment. (2)This study will also assess the impact of the emotional processing intervention on changes in pre and post treatment depression and anxiety, as well as fatigue.(3) This study will additionally measure the impact of the emotional processing intervention on cognitive functioning, specifically processing speed, attention and executive abilities. This will be accomplished through the completion of a neuropsychological battery prior to and following the completion of treatment.(4)Finally, the investigators will measure the impact of the intervention on quality of life and social functioning, utilizing a pre and post treatment assessment consisting of measures of self-efficacy, quality of life, functional abilities, and awareness.
Interventions
BEHAVIORALEmotional Processing Training
BEHAVIORALPlacebo Control
Sponsors
Kessler Foundation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* diagnosis of Multiple Sclerosis or Traumatic Brain Injury * Fluent in English * processing speed impairment (based on evaluation)
Exclusion criteria
* currently taking steroids and/or benzodiazepines * prior stroke or neurological diease * history of significant pyschiatric illness (for example, bipolar disorder, schizophrenia, or psychosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Epilepsy, Bipolar Disorder * significant alcohol or drug abuse history
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in scores on Facial Expression Identification Task (FEIT) | Scores will be assessed at two time-points, baseline (week 1) and post-intervention (week 8) | The FEIT assesses one's ability to correctly identify and discriminate emotions from faces |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in scores on Emotion Regulation Questionnaire (ERQ) | Scores will be assessed at two time-points, baseline (week 1) and post-intervention (week 8) | The ERQ is a self-report measure of the use of 2 emotional regulation strategies: cognitive reappraisal and expressive suppression |
| Change in scores on Satisfaction with Life Scale (SWLS) | Scores will be assessed at two time-points, baseline (week 1) and post-intervention (week 8) | The SWLS is a self-report measure of quality of life |
Countries
United States
Outcome results
None listed