Uroflowmetry Results and Vitamin D Levels

The Relationship Between Vitamin D Level and Lower Urinary Tract Symptoms in Women

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04405141

Enrollment

186

Registered

2020-05-28

Start date

2017-01-01

Completion date

2017-12-30

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcium Deficiency, Lower Urinary Tract Symptoms, Vitamin D Deficiency

Keywords

Lower Urinary Tract Symptoms, Vitamin D Deficiency, Calcium Deficiency

Brief summary

The investigators aimed to evaluate the relationship between LUTS and vitamin D with uroflowmetry parameters in female patients. They found no relation between vitamin D levels and LUTS in respect to uroflowmetry. However, in low vitamin D patients, Ca is related with urologic problems. The investigators believe that there is a need for studies emphasizing serum Ca levels in addition to vitamin D levels in patients with LUTS.

Detailed description

This retrospective cohort study included 186 female patients who admitted to LUTS. Demographic characteristics, medical history, calcium (Ca) and vitamin D including laboratory studies and uroflowmetry results as maximum urine flow rate (Qmax), average urine flow rate (Qav), and voided volume (V) were recorded. Patients were divided into two groups according to age (18-50 and ≥51) and vitamin D levels (\<20 and ≥20). Laboratory parameters, uroflowmetry results, were compared between groups. The study was approved by the local ethics committee (approval#22/06/2018-09.29-54132726-000-14136). The study was conducted in accordance to the Helsinki Declaration and Good Clinical Practices Guidelines.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

OTHER

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

Clinical diagnosis of low urinary tract symptom

Exclusion criteria

Urinary tract infection, Diabetes mellitus, Neurological disorder, Pregnancy Stone disease Other urinary system disorders.

Design outcomes

Primary

Measure	Time frame	Description
Uroflowmetry Results	12 months	There was no significant relationship between age, creatinine, Qmax, Qav, V and vitamin D level (P\>0.05).

Secondary

Measure	Time frame	Description
Vitamin D Levels	12 months	The mean D vitamin level was 21.19ng/ml. D vitamin was \<20 ng/ml in %55.9 patients. There was no difference in the levels according to the age of all patients.

Outcome results