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Local Recurrence Due to Rectal Cancer in Sweden

Local Recurrence Due to Rectal Cancer in Sweden - the Actual Incidence, Treatment and Outcome After Treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04404777
Acronym
LERIS
Enrollment
12000
Registered
2020-05-28
Start date
2022-07-01
Completion date
2027-06-01
Last updated
2025-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Neoplasms

Brief summary

The aim of this retrospective national registry study is to validate the reporting of local recurrence in the registry. Another aim is to identify preoperative risk factors for local recurrence. This can in turn indicate the need for a more intense follow-up. The treatment of local recurrence, including the impact of the multidisciplinary team conference (MDT) and the surgical procedure and the referral pathways of local recurrences will also be determined. We aim to evaluate treatment outcome after local recurrence for patients operated or treated between 2007-2018.

Interventions

PROCEDURETreatment for local recurrence with surgery or other treatments

All types of treatment for local recurrence will be evaluated

Sponsors

Sahlgrenska University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Rectal cancer with a curative intent

Exclusion criteria

* Rectal cancer without curative intent

Design outcomes

Primary

MeasureTime frame
Number of local recurrencesBetween 2007-2018
3 year survival3 years

Secondary

MeasureTime frameDescription
Percentage R0 resection after local recurrence1-2 months after initiated treatment
MDT effect on treatment of local recurrence1-3 months after diagnosis of recurrence
Reported metastases5 yearsNumber of patients with metastasis reported vs actual
MRI features at primary diagnosis and relation to recurrence2 monthsMRI evaluation by radiologist related to recurrence

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026