Rhegmatogenous Retinal Detachment
Conditions
Brief summary
Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment
Detailed description
The study takes place in the S.N. Fyodorov Eye Microsurgery Federal State Institution located in Moscow, Russian Federation. The study will include 50 patients with rhegmatogenous retinal detachment due to a horseshoe-tear. In addition to the standard ophthalmological examination, all patients will undergo wide-field optical coherence tomography to determine the extension and localization of the vitreoretinal traction zone. The obtained data will be used to planning the 1st step of laser-surgical treatment. All patients will undergo a combined laser-surgical technology, which includes 3 steps: 1) Nd-YAG laser excision of the vitreoretinal traction zone 2) pneumatic retinopexy (10% C3F8) 3) barrier laser photocoagulation around retinal break after retinal attachment. The patients are going to be followed up for at least 1 year, the main outcome measures are postoperative primary and final anatomic outcome, BCVA and complications.
Interventions
PROCEDURECombined laser-surgical technology of RRD treatment
1. Nd-YAG laser excision of the vitreoretinal traction zone 2. Pneumatic retinopexy (10% C3F8) 3. barrier laser photocoagulation around retinal break after retinal attachment (2-3 days after pneumatic retinopexy)
Sponsors
The S.N. Fyodorov Eye Microsurgery State Institution
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
1. Rhegmatogenous retinal detachment extending from the 9-o'clock to the 3-o'clock meridians. 2. Superior retinal break from 9 o'clock to 3 o'clock 3. Single retinal break not greater than 1 clock hours in size 4. Physically and mentally co-operated in post-operative head positioning 5. No (or minimal) proliferative vitreoretinopathy 6. None or mild vitreous hemorrhage.
Exclusion criteria
1. Severe concomitant eye pathologies (glaucoma, diabetic retinopathy, macular hole, traumas); OR 2. Ocular media opacities 3. Previous ocular surgeries 4. Age \<18 years 5. Previous retinal detachment (index eye)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Retinal reattachment rate | in 1 month after gas resorption | complete retinal re-attachment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anatomical success | 3, 6, 12 and 24 months post intervention | complete retinal re-attachment |
| Visual acuity | 3, 6, 12 and 24 months post intervention | ETDRS |
Countries
Russia
Contacts
Primary ContactMariiam Taevere, MD
Backup ContactLeonid Kryl, PhD, MD
Outcome results
None listed