Alcohol Use Disorder, Dyssomnias, Insomnia, Sleep Disorder
Conditions
Brief summary
The main goal is to study the effects of internet-delivered cognitive behavioural therapy with minimum guidance for comorbid sleep problems in alcohol use disorder, in routine addiction care.
Detailed description
Alcohol use disorder (AUD) is highly prevalent and a major contributor to the global burden of disease. Insomnia symptoms are very common among individuals with AUD, including those in recovery, which may in turn promote alcohol relapse. Specialization and silo phenomena in healthcare organization, separating addiction from other types of psychiatric care, means that individuals with AUD and comorbid sleep problems often have difficulty accessing evidence-treatment for the latter. Offering online treatment for sleep problems to individuals enrolled in traditional routine addiction care is an attractive and pragmatic approach to offering parallel treatments covering the full clinical presentation, which has not yet been evaluated. This pilot and feasibility trial will recruit n=25 from patients in routine addiction care with comorbid sleep problems and AUD, who will complete an online, ten-module, CBT-based treatment program with minimum guidance for sleep problems, tailored for individuals with AUD.
Interventions
BEHAVIORALCognitive behavior therapy
The ten modules cover: * Psychoeducation about sleep, sleep problems, and associations with alcohol * How to keep and use a sleep diary * Sleep hygiene * Sleep compression * Cognitive restructuring * Emotional regulation * Preparing for the future
Sponsors
Karolinska Institutet
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Enrolled patient at Stockholm Center for Dependency Disorders * Diagnosed alcohol use disorder * Self-rated sleep problem
Exclusion criteria
* Addiction to sedative or hypnotic medication * Psychoactive medication not yet 3-month stable in dose * Bipolar disorder * Psychotic disorder * Suicidality * Periodic Limb Movement Disorder (PLMD) * Sleep apnea
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Two-item Sleep Condition Indicator | Weeks 1 through 10 (max 15) | Total score of the two-item SCI, assessing last-week symptoms. Administered on the treatment platform. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Daily sleep diary | Weeks 1 through 10 (max 15) | Derived measures: last-week average sleep efficiency, time to fall asleep, time awake at night, total sleep time. |
| Daily alcohol diary | Weeks 1 through 10 (max 15) | Total consumed standard units of alcohol per week, during day and before bedtime |
| Alcohol Use Disorders Identification Test (AUDIT) | Change from baseline (pre-treatment), post-treatment (primary endpoint, 10-15 weeks after baseline), and follow-up three months after baseline.. | Total score |
| Sleep Condition Indicator | Change from baseline (pre-treatment), post-treatment (primary endpoint, 10-15 weeks after baseline), and follow-up three months after baseline.. | Change in score on the full and regular SCI. Administered through the online survey tool connected to regular patient records system. |
| Patient Health Questionnaire-9 (PHQ9) | Change from baseline (pre-treatment), post-treatment (primary endpoint, 10-15 weeks after baseline), and follow-up three months after baseline.. | Total score |
| Health-related quality of life (EQ5D) | Change from baseline (pre-treatment), post-treatment (primary endpoint, 10-15 weeks after baseline), and follow-up three months after baseline.. | Total score |
| Drug Use Disorders Identification Test (DUDIT) | Change from baseline (pre-treatment), post-treatment (primary endpoint, 10-15 weeks after baseline), and follow-up three months after baseline.. | Total score |
Countries
Sweden
Contacts
Primary ContactPhilip Lindner, PhD
Outcome results
None listed