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Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy

Root Canal Treatment of Compromised Teeth as Alternative Treatment in Patients Under Bisphosphonate Therapy: 60-month Results of a Prospective Clinical Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04399720
Enrollment
111
Registered
2020-05-22
Start date
2009-01-07
Completion date
2017-12-15
Last updated
2020-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bisphosphonate-Associated Osteonecrosis, Endodontically Treated Teeth, Periapical Abscess, Root Canal Infection

Keywords

success rate, survival rate, endodontic treatment

Brief summary

The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy . Clinical complications, success and survival rate was reported. Mean clinical parameters, clinical symptoms and presence of periapical radilucency were recorded.

Detailed description

The study was conducted in one University Endodontic Clinical Department - Dental School between January 2009 and December 2017. Root canal treatment was performed according previously reported operative protocols.

Interventions

PROCEDURERoot canal treatment

Root canal treatment using a standard manual k file instrumentation and carrier-based root canal filling technique

Sponsors

University of Bologna
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
40 Years to 85 Years

Inclusion criteria

* Patients affected by endodontic disease and able to attend a hygiene recall program

Exclusion criteria

* inability to attend a recall hygien program

Design outcomes

Primary

MeasureTime frameDescription
health patients5 yearsassessment of periapical index (PAI)

Secondary

MeasureTime frameDescription
Complications5 yearsextraction periapical re exacerbation during before the endline ( 5 years)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026