Cigarette Smoking, Cigarette Use, Electronic, Electronic Cigarette Use, Vaping
Conditions
Brief summary
This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco product use; and (2) facilitate adult smokers switching to e-cigarettes. There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile. For this substudy, young adult vapers (N=100) and adult smokers (N=100) will attend one laboratory session in which they will self-administer e-cigarette products varied according to within-subject e-cigarette factors (e.g., flavor, nicotine formulation).
Interventions
Participants will self-administer an experimenter-provided e-cigarette.
Sponsors
University of Southern California
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Vapers/E-cigarette Users * E-cigarette/vaping device use at least three days per week for at least 2 months * Regular use of e-cigarettes/vaping devices containing nicotine Cigarette Smokers * Daily cigarette smoking for at least two years * Currently smoke at least four cigarettes per day * Interested in trying an e-cigarette or current use of an e-cigarette
Exclusion criteria
Vapers/E-cigarette Users * Pregnant or breastfeeding * Desire to cut down on use of e-cigarette/vaping device Cigarette Smokers * Pregnant or breastfeeding * Current daily use of other combustible tobacco products (such as cigars)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Appeal | 1 hour | Self-report measures of product appeal will be completed following e-cigarette self-administration. |
| Sensory Appeal | 1 hour | Self-report measures of product appeal will be completed following e-cigarette self-administration. |
Countries
United States
Outcome results
None listed