Endotracheal Tube Cuff Pressure Measurement

Comparison of Two Different Measurement of Endotracheal Tube Cuff Pressure for Ventilatory Associated Pnemonia in Severe Brain Injured Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04397952

Enrollment

Registered

2020-05-21

Start date

2017-11-01

Completion date

2020-01-01

Last updated

2020-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endotracheal Aspiration, Morality, Trauma, Brain, Ventilator Associated Pneumonia

Keywords

pneumonia, cuff pressure, brain injury

Brief summary

The effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia.

Detailed description

Aim of this study is to evaluate the effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia of severe traumatic brain injured patients in a tertiary level intensive care unit.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

Patients with ASA classification of 1 - 2- 3 patients Patients required mechanical ventilation support for more than 48 hours Patients diagnosed with Traumatic brain injury

Exclusion criteria

Official patient relatives who rejected to give informed consent for the study Patients diagnosed with aspiration pneumonia during ICU follow up Patients diagnosed with Acute Respiratory Distress Syndrome Patients diagnosed with cavitary lung lesion Primary lung cancer Metastatic lung cancer Congenitally immune deficiency Leukopenia Neutropenia Tracheostomized patients Post cardiopulmonary arrest patients Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
PEEP	48.hour - 72.hour - 96.hour	Positive End Expiratory Pressure levels change from baseline at 48.hour, 72.hour and 96.hour during ventilatory support
Score	48.hour - 72.hour - 96.hour	Clinical Pulmonary Infection Score Change from baseline at 48.hour, 72.hour and 96.hour
CRP	48.hour - 72.hour - 96.hour	C Reactive Protein measurement change from Baseline at 48.hour, 72.hour and 96.hour
Oxygenation	48.hour - 72.hour - 96.hour	Fractional Inspiratory Oxygen levels change from baseline at 48.hour, 72.hour and 96.hour
Duration	30 days	Follow up duration in ICU
Ventilation	30 days	Mechanically ventilated period

Secondary

Measure	Time frame	Description
Bacterial distribution	0.hour - 48.hour - 72.hour - 96.hour	Bacterial distribution of tracheal aspirate culture
Mortality	30 days	Total mortality ratio during study period
Tracheal aspirate	0.hour - 48.hour - 72.hour - 96.hour	Tracheal aspirate sample for culture

Countries

Turkey (Türkiye)

Outcome results