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Contribution of Posterior Corneal Astigmatism to Total Corneal Astigmatism in a Sample of Egyptian Population

The Contribution of Posterior Corneal Astigmatism to Total Corneal Astigmatism Using Scheimpflug Analyzer (Pentacam ) in a Sample of Egyptian Population

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04393740
Enrollment
356
Registered
2020-05-19
Start date
2020-04-15
Completion date
2020-08-15
Last updated
2020-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Astigmatism

Brief summary

The magnitude of posterior corneal astigmatism was considered negligible due to the smaller difference in the refractive index between the cornea and the aqueous . though ,neglecting the posterior corneal astigmatism lead to errors during calculation of the toric iols (over or under estimation ) . so we aim to determine the percentage of contribution of posterior corneal astigmatism to total corneal astigmatism in a sample of Egyptian population using scheimpflug imaging (Pentacam ).

Detailed description

Astigmatism is a common vision condition that causes blurred vision. Astigmatism is an error of refraction in which incident parallel rays can't be focused to a single point .It could be corneal or lenticular astigmatism or both . Regarding Corneal astigmatism it is due to difference in the corneal curvature in the different meridian of both the anterior and posterior surface . The are 2 methods of studing corneal curvature : * Corneal topography which depend on placcido disc to study anterior corneal surface . * Corneal tomography is more precise in detecting anterior and posterior corneal curvature depending on Scheimpflug principle which uses a rotating Scheimpflug camera . Pentacam is a device which depend on Scheimpflug technique . The importance of studing the posterior corneal curvature includes : • The posterior corneal curvature is a more sensitive indicator of early keratoconus detection especially posterior corneal elevation. Previously, The change in the posterior corneal surface plays a more subtle role than the anterior corneal surface in optical performance because of the smaller difference in refractive indices between the cornea and aqueous, and it has been thought that the magnitude of PCA in the normal population is clinically negligible. Posterior corneal astigmatism (PCA) is important for better predictability of toric intraocular lens calculation to avoid under- or overestimation of toricity in intraocular lens (IOL) power calculations. But recently it has been demonstrated how neglecting PCA will lead to overcorrection of astigmatism in eyes with with-the-rule astigmatism (WTR) and undercorrection in eyes with against-the-rule astigmatism (ATR).(3) In our study we aim to Determine the contribution of posterior corneal astigmatism to total corneal astigmatism and the error in estimating total corneal astigmatism from anterior corneal measurements only using Scheimpflug analyzer (Pentacam ). Our patients will undergo Scheimpflug imaging using pentacam . From the corneal parameters displayed in pentacam we can calculate : * Anterior corneal astigmatism by substracting Ksteep -Kflat on the front surface * Posterior corneal astigmatism by substracting Ksteep-Kflat on the back surface. * Total corneal astigmatism is calculated by addition of anterior and posterior corneal astigmatism using vector analysis by using ASSORT vector calculator.\* * The percentage of contribution of posterior corneal astigmatism to magnitude of Total corneal astigmatism is then calculated . ASSORT vector calculator: Is a total planning and outcomes analysis software for astigmatism using Alpins method ,cheltman ,Victoria ,Australia .

Interventions

DIAGNOSTIC_TESTscheimpflug imaging using pentacam

corneal tomography imaging using pentacam device (based on Scheimpflug principle )

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

1. Patients with corneal astigmatism(±0.5D up tp ±4 D ) 2. Age (18-45 years ) 3. Refractive error (myopia up to -8D) 4. Hyperopia up to +4 5. Patients who have clear cornea . 6. Good quality Scheimpflug analyzer scans.

Exclusion criteria

1. Patients who have any corneal opacity . 2. Patients who underwent any Previous corneal surgery . 3. Patients who have Co existing corneal pathology. 4. Glaucomatus patients. 5. Patients with any Concomitant ocular disease . 6. Patients with History of previous ocular trauma .

Design outcomes

Primary

MeasureTime frameDescription
contribution of posterior corneal astigmatism to magnitude of total corneal astigmatism3 monthsto detect the contribution of posterior corneal astigmatism to total corneal astigmatism to avoid errors during calculation of toric Intra ocular lenses

Countries

Egypt

Contacts

Primary Contactalaa mo badawy, Msc
alaabadawy93@gmail.com01008858267
Backup Contactsarah A azzam, MD
Sarahazzam@ymail.com01227425601

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026