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Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care (LUS-COVID19)

Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04393402
Acronym
LUS-COVID19
Enrollment
14
Registered
2020-05-19
Start date
2020-03-20
Completion date
2022-12-31
Last updated
2025-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID

Brief summary

It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable patient, prone position and due to the high contagious nature of the disease. The lung ultrasound is an easy tool, fast (between 5 and 10 minutes) and as a limited training. In the context of the Sars-Cov2 epidemic, Buonsenso and al case report depict the first lung ultrasound for a Covid 19 patient. Peng and al in Intensive Care Medicine accentuate the usefulness of this particular technic. In the American Journal of Respiratory and Critical Care Medicine, a study has been published as a point-of-care, in which the doctors reported using the lung ultrasound with intensive and critical care patient. In Critical Care 2016, it has been showed that ultrasound allowed with neat precisions, to predict severe ARDS patient response to the prone position, all-cause. Another researchers team found a good correlation between lung ultrasound, the SOFA, APACHE II, CPIS score, and patient mortality. And a new applicability in the pulmonary recruitment by PEEP titration has been presented. The aim of this study is to evaluate the lung ultrasound in Covid19 ARDS.

Interventions

Patients with Covid-19 Disease and admitted in critical care unit will be performed a LUS

Sponsors

Centre Hospitalier Universitaire de Nice
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosed Sars-Cov2 patient, with PCR method qualitative or quantitative as usual. * Intensive or critical care admission * ARDS with PaO2/FiO2 \<300 at the admission * Ventilatory support or oxygen-therapy

Exclusion criteria

* Age \< 18 years-old * Pregnancy * Patient with tutor- or curatorship or in prison

Design outcomes

Primary

MeasureTime frameDescription
LUS applicability with COVID 1910 monthsIn dorsal position, or in prone position, the two hemithorax will be subdivided in 6 parts, and a score will be attributed with the following criteria : A-Lines (0 point), \> 3 B-lines (1 point), B-Lines coalscent (2 points), and pulmonary consolidation (3 points). For the echography we can use a convexe sonde, or a cardiac sonde.

Secondary

MeasureTime frameDescription
Radiographic correlation (chest Xray and tomodensitometry)10 monthsComparison between Xray / CT scan exam and LUS
LUS Mortality prediction10 monthsaccording to LUS score, ventilatory mode and parameters, medical history and bood analysis results
Prediction of Prone position response10 monthscomparison of LUS score depending of the position used for performing LUS

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026