Diffuse Parenchymal Lung Disease
Conditions
Brief summary
The primary intention of this study is to determine the diagnostic performance of ultra-low-dose CT (ULDCT) in diagnosis and follow-up of diffuse parenchymal lung disease (DPLD). We hypothesize that inspiratory and expiratory chest ULDCT has comparable diagnostic yield to standard dose chest High-resolution computed tomography (HRCT) and utility for follow-up of patients with known DPLD. We will study this hypothesis through the following aims: 1. Determine whether inspiratory and expiratory ULDCT are comparable to HRCT in identifying mosaic attenuation due to air-trapping. 2. Determine whether ULDCT is as good as HRCT for follow-up of patients with established DPLD to identify disease progression.
Interventions
None listed
Sponsors
Sheba Medical Center
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Inclusion criteria
1. suspected or known DPLD 2. referred to DPLD observation
Exclusion criteria
1\. other lung related diseases \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The primary outcome measure of this study is to determine the diagnostic performance of ULDCT in diagnosis of DPLD. | during the procedure/surgery | The diagnostic performance will be evaluated according to the biopsy results |
| The primary outcome measure of this study is to determine the prognostic performance of ULDCT in the follow up of DPLD. | during the procedure/surgery | The diagnostic performance will be evaluated according to the biopsy results |
Countries
Israel
Contacts
Primary ContactGal Varshavsky
Outcome results
None listed