Anemia of Pregnancy
Conditions
Brief summary
Women included between 18 and 45 years old, pregnant during their second or third trimester of pregnancy (calculated by a sure menstrual date and confirmed by a 1st trimesteric ultrasound) with hemoglobin level below 10.5 mg /dL.
Detailed description
All patients in the study were subjected to: 1. Detailed history was recorded. A proper history concerning age, sex, residence, socioeconomic status, onset, progression, and previous treatment of anemia was taken. Participants' socio-demographic characteristics including gravida and parity were documented, level of education, occupation, Diet, and information useful to determine the socioeconomic level was recorded. Information on previous pregnancies and children and history of chronic diseases were also recorded. 2. General examination; patients were clinically examined and gestational age (assessed by measuring the fundal height), weight was calculated for each participant. 3. Diagnosis of anemia by Complete blood count (CBC), Hb level and measuring hematocrit concentration. 4. Diagnosis of parasitic infection by stool analysis using suitable techniques. 5. Imaging including obstetric ultrasound (U/S) to assess fetal development. 6. Women with helminthic infections will be divided into groups Group (A): received iron + antiparasitic treatment as follows: * Patients who have STH received alzental 200mg tab 2 tabs single oral dose. * Patients who have Entamoeba or Giardia received flagyl 500mg tab twice daily for 5 days. * (B): received iron only.
Interventions
oral tablet twice daily after meals
500 mg oral twice daily
200 mg oral single dose
Sponsors
Study design
Eligibility
Inclusion criteria
* pregnant during their second or third trimester of pregnancy (calculated by a sure menstrual date and confirmed by a 1st trimesteric ultrasound) * hemoglobin level below 10.5 mg /dL
Exclusion criteria
* women with chronic diseases as diabetes, heart, renal, hepatic or endocrinological disorders * women diagnosed with blood diseases as hemoglobinopathy or vascular diseases as vasculitis. * Women with autoimmune diseases and those allergic to iron or antihelminsic treatment were also excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| correction of naemia | 6 weeks after treatment | hemoglobin level increased above 11 gm/dL |
Countries
Egypt