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Prognostic Factors of Patients With ADHF

Elevated Blood Monocyte Count Predicts 1 Year Poor Outcomes for Patients Admitted With Acute Decompensated Heart Failure

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04390919
Enrollment
362
Registered
2020-05-18
Start date
2011-08-02
Completion date
2015-02-16
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Decompensated Heart Failure

Keywords

monocyte count, heart failure, acute decompensated heart failure, all-cause death

Brief summary

To explore the prognostic indicators for patients with ADHF

Detailed description

According to ESC Guidelines for the diagnosis of acute heart failure 2008, patients with ADHF were diagnosed, and their medical history, laboratory examination and treatment plan were retrospectively analyzed, and the patients were followed up for 1 year. The 1-year outcomes of patients were analyzed to explore the prognostic indicators for patients with ADHF

Interventions

OTHERelevated monocyte count

The monocyte count at admission was higher than 0.445×10\*9 cells/L

Sponsors

Chongqing Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 94 Years
Healthy volunteers
No

Inclusion criteria

* Patients with ADHF diagnosed according to ESC Guidelines for the diagnosis of acute heart failure 2008

Exclusion criteria

* disorders of the hematopoietic system, history of cancer and/or previous treatment with chemotherapy, the infection caused by various pathogens, chronic inflammatory conditions, glucocorticoid therapy and/or histories of glucocorticoid use 3 months before the admission and acute myocardial infarction or coronary revascularization within the past 6 months. Also, patients who did not have a differential WBC count or who were lost to follow-up were excluded.

Design outcomes

Primary

MeasureTime frameDescription
all-cause death1 yearThe primary end point was one-year all-cause death

Secondary

MeasureTime frameDescription
HF-related rehospitalization1 yearthe secondary end point was one-year HF-related rehospitalization.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026