Cardiovascular Diseases, Cardiovascular Risk Factor, COVID-19, Heart Failure
Conditions
Keywords
COVID-19, Cardiovascular Diseases, Cardiovascular Risk Factor, Heart Failure
Brief summary
Background: Coronavirus disease (COVID-19) is a tremendous challenge the modern world has never seen before and is overwhelming the capacities of healthcare systems worldwide. Patients with cardiovascular diseases, heart failure in particular, and cardiovascular risk factors seem to be at a very high risk if affected by COVID-19 - and vice versa there are more and more reports of cardiac manifestations with the viral disease. Aim: The purpose of the study is to characterise the clinical course of adult inpatients with COVID-19 and concomitant cardiovascular affection in a worldwide, multicentre PCHF registry. Methods: Retrospective and prospective data analysis. Data on demographic, clinical, selected laboratory, electrocardiography and echocardiography parameters, treatment and outcome will be collected. The principal investigator provides dedicated electronic case report form. The primary outcome is in-hospital mortality. The secondary endpoints will be ICU length of stay, hospital length of stay, the need and duration of invasive mechanical ventilation, cardiovascular hospitalisation after 3 and 6 months from index hospitalisation, all-cause and cardiovascular mortality after 3 and 6 months from index hospitalisation.
Interventions
None listed
Sponsors
Wroclaw Medical University
University of Zurich
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult inpatients (≥18 years old) with laboratory-confirmed COVID-19.
Exclusion criteria
* Age \<18 years old. * Outpatients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| In-hospital mortality. | Hospitalization period, assessed up to 30 days | All-cause and cardiovascular mortality during index hospitalization. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The length of stay in the intensive care unit. | Hospitalization period in the ICU, assessed up to 30 days | The duration of hospitalization on the intensive care unit. |
| The duration of hospitalization. | Hospitalization period, assessed up to 30 days | The total length of stay in the hospital. |
| The need and duration of invasive mechanical ventilation. | Hospitalization period, assessed up to 30 days | — |
| Hospitalization for cardiovascular causes or cardiovascular deaths within 3 months after hospitalization. | 3 months | — |
| Hospitalization for cardiovascular causes or cardiovascular deaths within 6 months after hospitalization. | 6 months | — |
Countries
Switzerland
Contacts
Primary ContactMateusz Sokolski, MD, PhD
Backup ContactSander Trenson, MD
Outcome results
None listed